Open access
Jul 2026
Targeting the Adenosine—Adenosine Deaminase-1 Axis to Restore HIV-Specific CD8+ T Cell Function 2309228
This approach provides a framework for targeting ADO-mediated immune suppression of CD8+T cells in HIV and other disease landscapes, including cancer, and establishes targeted ADA-1 delivery as a novel strategy to enhance CD8+ T-cell function.
Arden O. Edgerton, Dillon O'Neill, David Joyner et al.
· Journal of Immunology · 0 citations