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Open access Jul 2026

Network-based discovery of regulatory drivers of cognitive decline in alzheimer’s disease

Network analysis uncovered significant differences in regulatory connectivity between AD and controls, with ZNF225, ZNF849, and ZNF548 emerging as AD-specific regulatory hubs and several key regulatory edges showed significant correlations with longitudinal cognitive decline, supporting their clinical relevance.

D. Anwer, Arina A, Agata Marchi et al. · 1 citation

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