Author

Arjun Patel

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Open access Oct 2026

Adaptive respiratory bypass restores oxidative metabolism in NADH dehydrogenase-deficient Escherichia coli

Nicotinamide adenine dinucleotide is central to the cellular redox network and continuously cycles between its oxidized (NAD⁺) and reduced (NADH) forms. Membrane-bound NADH dehydrogenases are the primary NADH-oxidizing enzymes and principal entry point for reducing equivalents into the bacterial respiratory chain. Whil...

Arpita Biswas, Arjun Patel, Nikita Goel et al. · bioRxiv · 0 citations

Review Open access Oct 2026

Metabolic modeling: the link between AI and multi-omics data to accelerate the discovery of antibiotic-resistant traits in ESKAPE pathogens

ABSTRACT The development of predictive understanding of bacterial resistance to antibiotics is one of the greatest challenges of modern medicine. Genome-scale metabolic models (GEMs) are mathematical representations of the metabolic network of a given organism assembled from genomic data that predict cellular activity...

N. Muzahid, Arjun Patel, Mason Raymond et al. · Infection and Immunity · 0 citations