Open access
Sep 2026
Single-cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti-SSA antibodies and aberrant B cell populations.
A two-disease model of SjD is supported and transitional B cells are highlighted as both a key biomarker and a therapeutic target, highlighting substantial biological heterogeneity within SjD.
G. Urbanski, K. Taylor, E. Flynn et al.
· Arthritis & Rheumatology · 0 citations