Open access
Sep 2026
Integrative structure of norovirus NS3 suggests a role in RNA transport
Human noroviruses (HuNoVs) are the leading global cause of acute gastroenteritis, yet no vaccines or antiviral therapies are currently approved. The non-structural protein NS3 is a membrane-bound AAA+ ATPase of superfamily 3 (SF3) with multiple proposed roles in the norovirus replication cycle. However, the structure...
Meryl Haas, T. Hoeksma, J. Mills et al.
· Nature Communications · 0 citations