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Author

Arnab Ghosh

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Open access Sep 2026

Study of Estrogen Receptor-Mediated PGx-eQTLs Identifies Genetic Determinants of Breast Cancer Endocrine Therapy Response

Endocrine therapy remains the cornerstone of treatment for estrogen receptor alpha (ERα)-positive breast cancer, yet the relationship between individual genetic background and molecular response to ERα-targeted therapy remains incompletely understood. Using a well-characterized panel of lymphoblastoid cell lines (LCLs)...

M. Meng, Arnab Ghosh, Huan-Yao Gao et al. · 0 citations
Open access Sep 2026

Single-cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti-SSA antibodies and aberrant B cell populations.

A two-disease model of SjD is supported and transitional B cells are highlighted as both a key biomarker and a therapeutic target, highlighting substantial biological heterogeneity within SjD.

G. Urbanski, K. Taylor, E. Flynn et al. · 0 citations

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