Diagnostic Accuracy and Renal Safety of Carbon Dioxide Angiography in Lower Limb Angiography: A Systematic Review and Meta-Analysis
Background/Objectives: Iodinated contrast media (ICM) used in lower limb angiography carry risks of contrast-induced nephropathy (CIN) and allergic reactions, particularly in patients with peripheral arterial disease (PAD) and renal dysfunction. Carbon dioxide (CO2) angiography offers a potential non-nephrotoxic altern...