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Review Open access Sep 2026

Biological age measured by DNA methylation clocks and reproductive history: Systematic review and meta-analysis.

Reproductive history has implications for long-term health, with menopausal timing and parity associated with chronic disease risk. DNA methylation (DNAm) clocks are biomarkers of aging and estimate epigenetic age acceleration (EAA) in reproductive tissues and systemically. DNAm clocks provide mechanistic insight into...

M. Simonson, Wei-Lan Wang, Jian-Hua Tay et al. · 0 citations

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