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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Aruna S. Jaiswal

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Open access Aug 2026

PCNA–RECQL5–RPRD1B recruit repair components to stressed replication forks to promote survival of BRCA1-deficient cancer cells

Abstract Given their defect in homologous recombination, BRCA1-deficient cancers use polymerase theta (POLQ) microhomology-mediated end joining (MMEJ) for repair of stressed replication forks. We found that BRCA1-deficient cells repress microRNA (miR) 4485-3p, and reconstituting expression of this miR resulted in the d...

M. T. Tran, Elizabeth A. Williamson, Aruna S. Jaiswal et al. · 0 citations

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