A wide range of chronic illnesses, including metabolic, autoimmune, neurodegenerative, and malignant conditions, are caused by the dysregulation of inflammation, a complex, multi-scale biological defense mechanism. Despite their clinical efficacy, current pharmacotherapies such as NSAIDs, corticosteroids, and biologics...
This research highlights the feasibility of using thiazole-derived AChE, BuChE, MAO-B, and amyloid-β inhibitors as scaffold pharmacophores for developing novel drugs to treat Alzheimer's disease and provides vital guidance on the development of future drugs.
Geetanjali Chaudhary, Deepika Paliwal, Aman Thakur et al.· Mini-Reviews in Medical Chem...· 0 citations
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