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Author

Ashley P. Ghiaseddin

2 papers indexed here

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Open access Aug 2026

18 TTFields with maintenance temozolomide/pembrolizumab versus TTFields with maintenance temozolomide/placebo for newly diagnosed glioblastoma: the phase 3 EF-41/KEYNOTE D58 trial

With the current standard-of-care for glioblastoma (maximal safe resection followed by radiotherapy with concurrent TMZ, then maintenance temozolomide/TTFields), median overall survival (OS) is approximately 21 months. Immune checkpoint inhibitors have not demonstrated meaningful clinical benefit in glioblastoma,...

G. Borst, David D. Tran, Ashley P. Ghiaseddin et al. · 0 citations
Open access Aug 2026

CLTR-03 IMPACT-MET: A PHASE I STUDY TO ASSESS SAFETY AND FEASIBILITY OF IL-8 RECEPTOR MODIFIED, PATIENT-DERIVED, ACTIVATED CD70 CAR T CELL THERAPY IN ADULTS WITH BRAIN METASTASES FROM PRIMARY CANCERS

This study will evaluate the safety and feasibility of 8R-70CAR T cells in BM patients and may inform on the future development of 8R-70CAR T cell therapy in this population.

Taryn King, A. Fares, P. Deleyrolle et al. · 1 citation

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