Ashlynn A. Gallagher

α2δ-2 mediates coupling of presynaptic calcium entry to vesicle release in hippocampal parvalbumin-expressing interneurons

Using electrophysiological recordings from genetically modified mice, α2δ-2 functionally couples calcium entry to vesicle release from parvalbumin-expressing cells, which provides a potential explanation for the seizure phenotype of α2δ-2 mutant mice and illuminates the broader roles of α2δ proteins in neuronal functio...