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Author

Ashok Kumar

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Sep 2026

Identification of repositioned inhibitors of pan-cancer proteasomal target as potential anti-proliferative candidates using a computational therapeutics approach.

UBE2C (Ubiquitin-Conjugating Enzyme E2C) is an E2 ubiquitin-conjugating enzyme involved in the ubiquitin-proteasome system which plays a crucial role in protein degradation and regulation of cell cycle. Overexpression of UBE2C can lead to mitotic defects, genomic instability and uncontrolled cell division, contributing...

Parminder Singh, Ashok Kumar, Nilambra Dogra · 0 citations

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