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Open access Aug 2026

Dihydropyrimidinone–isatin hybrids as potent inducers of cell-cycle arrest and caspase-dependent apoptosis in MV4-11 acute myeloid leukemia cells

Overall, the cytotoxic effects of 7k on MV4-11 cells are attributed to the coordinated induction of ROS-mediated oxidative stress, G0/G1 cell cycle arrest, and caspase-dependent apoptosis, highlighting its promising antiproliferative potential.

Preeti, Asif Raza, Jashandeep Kaur et al. · 0 citations