Quantitative Analysis of Active Compounds in a Three-Component Pharmaceutical Formulation Using Multivariate Calibration Methods
A rapid, simple, and cost-effective spectrophotometric method combined with multivariate chemometric calibration was developed for the simultaneous determination of paracetamol (PRC), caffeine (CFN), and propyphenazone (PRPN) in a ternary pharmaceutical formulation without any prior separation step. The direct UV spect...