Aslı Azizoğlu

Orthogonal inducible transcriptional control systems for investigation of gene-gene interactions in Saccharomyces cerevisiae

Genes function within dense networks of interactions, where phenotypes often depend on the relative expression levels rather than loss or gain of function. Most genetic interactions in Saccharomyces cerevisiae have been identified using deletions or overexpression, leaving dosage-dependent interactions underexplo...