Assiya Mamedova

Spectrum of Germline Mutations in BRCA1 and BRCA2 Genes in Patients with Breast Cancer and Women with a Family History in the Kazakh Population

Introduction: Germline mutations in the BRCA1 and BRCA2 genes are an important hereditary risk factor for the development of breast cancer. The spectrum of pathogenic variants of these genes is characterized by pronounced ethnic and population specificity, including the presence of founder mutations. Data on the spectr...