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Atsushi Onoe

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Case report Open access Oct 2026

Secondary pulmonary alveolar proteinosis mimicking progression of interstitial lung disease during treatment for adult-onset still’s disease

Rationale: Secondary pulmonary alveolar proteinosis (sPAP) is a rare disorder caused by impaired surfactant clearance due to alveolar macrophage dysfunction and is often associated with hematologic disorders or immunosuppressive therapy. In patients with connective tissue disease–associated interstitial lung disease (C...

Takashi Yamane, Taisuke Fujita, Atsushi Onoe et al. · 0 citations

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