Reconciling Cryo-EM and Crystallographic Views of RNA Folding through Atomistic Structure-Based Simulations: Roles of Ionic Conditions and Truncation of Flexible Elements.
The STEM framework demonstrates how information from condition-dependent experiments can be integrated to yield a coherent mechanistic picture of RNA folding by demonstrating how information from condition-dependent experiments can be integrated to yield a coherent mechanistic picture of RNA folding.