FORMULATION AND EVALUATION OF A CLOTRIMAZOLELOADED ETHOSOMAL GEL FOR ENHANCED TRANSDERMAL ANTIFUNGAL ACTIVITY
Background: Fungal infections represent a substantial global health burden, affecting nearly one billion people worldwide. Clotrimazole, a broad-spectrum antifungal agent, has been a cornerstone of topical therapy; however, its clinical utility is significantly constrained by poor dermal bioavailability and inadequate...