Aug 2026
Novel salicylamido sulfonamides as CD73 immune checkpoint inhibitors: Synthesis and in vitro biological evaluation.
In silico ADME analysis indicated that both lead compounds possess favourable drug-like properties, with no Lipinski's rule-of-five violations, balanced lipophilicity, and acceptable predicted oral absorption, supporting their pharmacokinetic potential.
Dinesh Krishna Narukulla, Shrilekha Chilvery, C. Godugu et al.
· Bioorganic & Medicinal Chemi... · 0 citations