Aya I. Abd El-hameed

Exploration of novel hydroxamic acid-based candidates integrating chalcone scaffold cap as multitarget HDAC inhibitors: design, anti-prostatic cancer assessment, in silico docking and molecular dynamic simulation

The potential use of this compound for treating prostate cancer with bone metastasis is suggested, as its high affinity for HDACs and an atomistic standard 100 ns dynamic simulation supported the stability of these interactions.