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Author

Ayesha Umair

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Open access Sep 2026

Trimethoprim suppress phage activity and reduces toxin production in a clinical STEC strain, even in the presence of DNA-damaging antibiotics

How acid exposure and trimethoprim both potently suppress phage production ∼100-fold, even in the presence of antibiotics that increase phage activity is described, forming a key lead in finding a new option to treat these infections, without risking potentially lethal complications.

Ayesha Umair, Alexander P. Hynes · 0 citations

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