Author

Ayhan Bilir

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Open access Sep 2026

Differential Effects of Carboplatin, Metformin, and Boric Acid on Cell Viability, Migration, and Oxidative Stress in MCF-7 Breast Cancer and CRL-4010 Normal Mammary Epithelial Cells

Background/Objectives: Oxidative stress is a key contributor to breast cancer (BC) progression and therapeutic response. Although carboplatin is widely used in BC treatment, the effects of combining carboplatin with metformin and boric acid (BA) on cellular redox homeostasis remain poorly understood. This study investi...

Nilüfer Ece Süren, Burcu Biltekin, S. Değirmencioğlu et al. · Biomedicines · 0 citations

Review Open access Sep 2026

Personalized mRNA Neoantigen Vaccines in Cancer: Linking Precision Antigen Selection, Immune Remodeling, and Checkpoint Blockade

Personalized mRNA neoantigen vaccines represent an emerging form of precision cancer immunotherapy designed to generate de novo T-cell responses against patient-specific tumor mutations. Their therapeutic activity, however, depends not only on neoantigen selection and vaccine-induced immune priming but also on whether...

T. Demircan, Berna Yıldırım, Halil İbrahim Ünsal et al. · International Journal of Mol... · 0 citations