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Author

Ayman Salama

2 papers indexed here

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Sep 2026

Nanovesicular Spanlastics Thermosensitive Gel for the Ocular Delivery of Voriconazole: Development, Ex Vivo Transcorneal Permeability, and In Vivo Evaluation in a Rabbit Model of Fungal Keratitis

Fungal keratitis remains a leading cause of corneal blindness and eye loss worldwide. Conventional antifungal preparations such as those of voriconazole (VCZ) are often limited by rapid precorneal drug loss and poor corneal penetration, leading to suboptimal therapeutic outcomes. This study aimed to address these limit...

G. Soliman, Ayman Salama, Mona Qushawy et al. · 0 citations
Open access Sep 2026

Nanosized Bilosomes as a Potential Platform for Improved Therapeutic Efficacy of Capecitabine Against Colon Cancer in Rats: Formulation, Evaluation, and Optimization

Background/Objectives: Colorectal cancer is a leading cause of global cancer-related mortality. Capecitabine, a 5-fluorouracil prodrug, effectively targets colorectal cancer but suffers from an extremely short half-life, requiring frequent administration. Bilosomes (membrane-stabilized bile salts) are vesicular systems...

Mahmoud Mostafa, Abd El Hakim Ramadan, A. El-Shenawy et al. · 0 citations

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