Review
Open access
Sep 2026
Pediatric DOCK8 Deficiency Beyond Infections and Atopy: An Immunoactinopathy with Immune Dysregulation and Multisystem Involvement
Highlights What are the main findings? This tertiary-center cohort supports viewing pediatric DOCK8 deficiency as an actin cytoskeleton-related IEI with overlapping infectious, allergic, immune-dysregulatory, and systemic manifestations. Beyond eczema and recurrent infections, the cohort included cytopenias, autoimmuni...
Figen Çelebi Çelik, N. Yüksel, Ömer Akçal et al.
· Children · 0 citations