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Ayon Mukherjee

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Preprint Aug 2026

Efficient Response-Adaptive Randomization for Multi-arm Trials with Prioritized Composite Endpoints

The efficient randomized-adaptive design attains the minimal possible variance of the allocation proportion for any pre-specified target and has been extended from two to several treatment arms, but both versions target a single response. Confirmatory trials increasingly rely on several prioritized endpoints, typically...

Ayon Mukherjee · 0 citations

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