Ayu Inoue

[A novel human 3D steatohepatitis model recapitulating disease progression for evaluating the efficacy and mechanism of action of MASH therapeutics].

Fatty liver disease prevalence is rising in Japan due to Westernized diets. Despite extensive efforts, treatments for metabolic dysfunction-associated steatohepatitis (MASH), which carries high cirrhosis risks, remain unapproved in Japan. A primary cause of clinical failure is the inability of animal models to accurate...