Persistence of immune responses 5 years after vaccination with a single dose of typhoid conjugate vaccine (TCV) in Nepalese children.
BACKGROUND A single-dose typhoid conjugate vaccine (TCV) has been recommended in endemic settings. Here we report the 5-year immunogenicity results post a single dose of TCV in Nepal. METHODS We conducted a participant- and observer-blinded randomised trial (RCT) in Lalitpur, Nepal (2017-2021) (ISRCTN43385161). 20,01...