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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

B. Baune

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4 papers indexed here

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Open access Aug 2026

A Delphi-method-based consensus for clinical domains and assessment of the inflammatory subtype of major depressive disorder from the ASPIRE study.

BACKGROUND Elevated inflammatory biomarkers have been consistently associated with a subset of depressive symptoms, particularly atypical and energy-related features, as well as antidepressant treatment resistance. This evidence has supported the definition of an inflammatory subtype of major depressive disorder (ISMDD...

B. Vai, T. Cazzella, C. Monopoli et al. · 1 citation
Open access Aug 2026

Comparing trajectories of cognitive functioning in treatment-resistant and non-resistant depression: a multicentre linear mixed-effects analysis.

BACKGROUND Impaired cognitive functioning is a severe symptom in major depressive disorder (MDD). Recent evidence suggests it may be a central characteristic in its treatment resistant form (TRD), potentially constituting a clinical marker for treatment resistance and a target amenable to intervention. To date, cogniti...

V. T. Wahner, T. Lange, Inga Stonner et al. · 0 citations
Open access Sep 2026

708. From molecules to meaning: metabolomic and transcriptomic pathways to overcoming treatment resistance

Abstract Background Treatment resistance remains a major barrier to improving outcomes in severe psychiatric disorders, reflecting substantial biological heterogeneity that is not captured by symptom-based diagnosis alone. Emerging multi-omics approaches—particularly metabolomic profiling combined with transcriptome-in...

B. Baune · 0 citations
Review Open access Sep 2026

Pharmaco-multiomics in major depressive disorder: a narrative review and proposed translational framework for difficult-to-treat and treatment-resistant depression

Current clinical application should remain limited to systematic medication and interaction review, drug-specific guideline-supported PGx, and indication-specific TDM, with a future-state architecture and staged evidence-to-implementation framework for DTD/TRD.

B. Baune · 0 citations

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