Valproic acid remodels phosphatidylglycerol homeostasis and epithelial-macrophage crosstalk in inflammatory signaling
Summary Pulmonary surfactant lipids support lung homeostasis and innate immunity, and their dysregulation contributes to acute respiratory distress syndrome. Whether mitochondrial phosphatidylglycerol (PG) biosynthesis influences epithelial lipid secretion and inflammatory responses remains unclear. Using A549 cells, w...