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B. Borlaug

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Oct 2026

GLP-1 receptor agonist treatment and cardiovascular outcomes following aortic valve replacement: a nationwide observational study.

BACKGROUND GLP-1 receptor agonists reduce major adverse cardiovascular events among patients with diabetes, overweight, and obesity. Whether these benefits extend to patients undergoing aortic valve replacement (AVR) for severe aortic stenosis (AS) remains unknown. Thus, we investigated the association between GLP-1 re...

L. Krasniqi, M. Hamandi, P. Mortensen et al. · 0 citations
Open access Sep 2026

Sotatercept Improves Right Heart Mechanics Despite Reduced Myocardial Contractility in Pulmonary Arterial Hypertension - A Prospective Exercise Hemodynamic Study

Background: The right ventricular (RV) response to pressure overload is a crucial determinant of outcomes in pulmonary arterial hypertension(PAH). Sotatercept improves clinical outcomes, but its effects on the RV have been inconsistent. We sought to evaluate the effects of sotatercept on load-independent measures of RV...

Y. Reddy, S. Kazui, W. Miranda et al. · 0 citations
Open access Aug 2026

Severe Infections as a Novel Risk-Enhancing Factor for Incident Heart Failure.

BACKGROUND We examined the relationship between infection-related hospitalization (IRH) and heart failure (HF) in a large clinical health system and assessed whether IRH improved prediction beyond HF risk equations. METHODS We studied 80 880 adults (14 150 with IRH and 66 730 age- and sex-matched comparators) aged ≥1...

R. Demmer, Brandon R Grossardt, Sadiya S. Khan et al. · 0 citations
Open access Aug 2026

Left atrial remodeling and functional maladaptations in obesity: an invasive pressure-volume analysis

In patients undergoing AF ablation, higher BMI is associated with a predominantly load-related pattern of LA remodeling, characterized by larger LA volume and pressures, greater cyclic wall stress, and a rightward shift of the estimated pressure–volume relationship.

L. Monzo, B. Borlaug, K. Kroupova et al. · 0 citations
Sep 2026

Exercise stress echocardiography for diagnosis of heart failure with preserved ejection fraction: a multicentre study.

Addition of LA strain imaging with optimized rule-in or rule-out values improves diagnostic triage by expanding non-invasive rule-in/rule-out classifications while identifying patients who still require invasive testing in the evaluation of HFpEF.

T. Harada, Yogesh N. V. Reddy, H. Sorimachi et al. · 0 citations
Jul 2026

Cardiac mechanical efficiency in patients with cardiogenic shock.

Early TTE-derived mCE was independently associated with short- and long-term mortality in CS, particularly in acute coronary syndrome-related CS, and captured the interaction between ventricular remodeling and mechanical performance underlying high-risk phenotypes.

K. Berg-Hansen, O. Hørsdal, H. Wiggers et al. · 0 citations

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