Author

B. Bosch

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Open access Aug 2026

Monoclonal antibodies target conserved S1B epitopes across deltacoronaviruses to inhibit porcine deltacoronavirus infection

This study generated and characterized a panel of monoclonal antibodies targeting the PDCoV S1 protein and identified five S1B-specific neutralizing antibodies that cross-react with S1B proteins from multiple human- and avian-origin deltacoronavirusess.

Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al. · mBio · 0 citations

Open access Aug 2026

Spike and host glycan determinants of HKU1 airway tropism

It is shown that spikes from both serotypes of HKU1 preferentially bind 9-O-acetylated α2,8-linked disialosides, and molecular dynamics simulations indicated that membrane-embedded GT3, but not GD3, presents its glycan chain in a geometry compatible with S1A-mediated engagement.

Robert Creutznacher, Louisa Elizabeth Wallace, Oliver J. Debski-Antoniak et al. · bioRxiv · 0 citations