Author

B. Bravi

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Open access Aug 2026

A Delphi-method-based consensus for clinical domains and assessment of the inflammatory subtype of major depressive disorder from the ASPIRE study.

BACKGROUND Elevated inflammatory biomarkers have been consistently associated with a subset of depressive symptoms, particularly atypical and energy-related features, as well as antidepressant treatment resistance. This evidence has supported the definition of an inflammatory subtype of major depressive disorder (ISMDD...

B. Vai, T. Cazzella, C. Monopoli et al. · Brain, behavior, and immunit... · 1 citation

Open access Aug 2026

Lifespan brain structural variation reveals shared organization across mental health conditions

Large-scale evidence is provided that structural deviations across NDPCs are systematically constrained by the brain's intrinsic architecture, providing a framework for reconciling individual variability with transdiagnostic similarities and motivates an integrative, systems-level understanding of mental health.

M. Hettwer, A. Saberi, G. Shafiei et al. · medRxiv · 0 citations

Open access Jul 2026

CLOCK 3111T/C Polymorphism and Sex Moderate the Effect of Childhood Trauma on White Matter Microstructure in Bipolar Disorder

Background. Bipolar disorder (BD) is characterized by circadian rhythm disruptions, contributing to mood instability and recurrence. These rhythms are regulated by clock genes in the suprachiasmatic nucleus, including the CLOCK 3111T/C (rs1801260) polymorphism that has been linked to delayed sleep phase, insomnia, and...

F. Nozza, B. Bravi, L. Fortaner-Uyá et al. · Genes · 0 citations