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Author

B. Brüne

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3 papers indexed here

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Open access Sep 2026

Decreased FSP1 expression under chronic hypoxia sensitizes human macrophages towards ferroptosis

Ferroptosis, an iron-dependent cell death, emerged as a new therapeutic approach to treat diseases such as cancer or diabetes. Several pathological conditions are characterized by the appearance of chronic hypoxia, which is known to attract immune cells, especially monocytes and macrophages. Therefore, we investigated...

Anja Wickert, Anna Schwantes, Yara Shadid et al. · 0 citations
Review Open access Oct 2026

NRF2: sensing stress, shaping immunity - keeping inflammation quiet and antigens out of sight

The Cap ‘n’ Collar basic leucine zipper transcription factor NRF2 has been linked to inflammation almost since its identification as the master regulator of oxidative stress responses. Early studies demonstrated systemic inflammation and dysregulated immune responses following NRF2 loss. Initially, NRF2 was thought t...

Y. Benatzy, B. Brüne · 0 citations
Open access Jul 2026

Phenotypic and Metabolic Signatures in Chronic Autoimmune Inflammation 2308477

Several immune and metabolic dysregulations in SLE and PsA patients are described, which could be used as potential biomarkers for disease progression and therapeutic intervention.

Blerina Aliraj, B. Brüne, M. Köhm et al. · 0 citations

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