Multiscale assessment of glucocorticoid-induced alterations across bone marrow and mineralized bone in human iliac crest biopsies.
BACKGROUND Glucocorticoid-induced osteoporosis (GIOP) is associated with a fracture risk that exceeds what would be expected based on bone mineral density (BMD) alone, suggesting impaired bone quality. In contemporary clinical practice, patients receiving glucocorticoids are typically treated concomitantly with anti-os...