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B. Dozières

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Open access Oct 2026

Multimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance-guided laser interstitial therapy: A pediatric single-center retrospective study.

OBJECTIVE This study was undertaken to evaluate seizure outcomes after magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ). METHODS We conducted a retrospect...

L. Guida, E. Losito, Sebastian Rodrigo et al. · 0 citations
Open access Aug 2026

Early sodium channel blocker initiation is associated with better outcomes in KCNQ2 disorders.

Earlier SCB initiation was associated with earlier seizure offset and more favourable developmental outcomes, underscoring the importance of early genetic diagnosis and timely SCB therapy, and the use of SCBs, particularly CBZ and OXC, as first-line therapy in (LOF) KCNQ2-DEE and SeL(F)NE is supported.

C. Millevert, M. Hairabedian, Samuel Dahan et al. · 1 citation

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