Author

B. E. Ekundayo

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Review Open access Oct 2026

Targeting the IRE1α/XBP1 pathway in type 2 diabetes mellitus: from ER stress signaling to therapeutic opportunity

To respond to protein misfolding in the endoplasmic reticulum (ER), cells trigger the unfolded protein response (UPR) to re-establish proteostasis. However, unresolved UPR results in chronic ER stress, which is critical to the development and advancement of type 2 diabetes mellitus (T2DM), a multifactorial disease whos...

O. T. Obafemi, A. Ayeleso, B. E. Ekundayo et al. · Molecular Biology Reports · 0 citations

Review Open access Sep 2026

Neuroprotective Effect of Morin Against Chemical‐Induced Neurotoxicities and Neurodegenerative Disease Models

Morin (3,5,7,2′,4′‐pentahydroxyflavone) is a dietary flavonol with broad neuroprotective, anti‐inflammatory, and antioxidant actions across central and peripheral nervous system models. This synthesis consolidates evidence from in vitro and rodent studies—covering neurodegenerative proteinopathies (Alzheimer's, Parkins...

B. E. Ekundayo, Motunrayo Comfort Ekundayo, S. Alonge et al. · European Journal of Neurosci... · 0 citations

Open access Sep 2026

Acetone Extract of Annona Muricata Linn Leaf Counteracts Hyperglycemia-Associated Metabolic Dysregulation by Modulating Oxidative Stress and Hepatic Carbohydrate Metabolism in Streptozotocin-Induced Diabetic Rats.

Annona muricata is widely recognized for its rich phenolic composition and potent antioxidant activity, suggesting therapeutic potential in diabetes management. This study investigated the mechanistic antidiabetic effects of acetone extract of A. muricata leaf on hepatic carbohydrate metabolism, oxidative stress, and h...

Benjamin Olusola Omiyale, B. E. Ekundayo, Olutosin Samuel Olusola et al. · Cell Biochemistry and Biophy... · 0 citations