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Open access Sep 2026

466. Neurotransmitter disturbances and relationship to short- and long-term outcome in initially antipsychotic-naïve patients with first-episode psychosis

Abstract Background Rodent models of schizophrenia suggest that combined dopaminergic, glutamatergic and GABAergic neurotransmitter disturbances play a key role in the illness pathophysiology, but whether this translates to patient samples is unknown. Furthermore, non-dopaminergic neurotransmitter disturbances may be m...

K. Bojesen, C. Lemvigh, E. Rostrup et al. · 0 citations
Open access Aug 2026

Inflammation in pregnancy and child neurodevelopment: A trio polygenic score and Mendelian randomization study in the Norwegian mother, father and child cohort.

BACKGROUND Inflammation in pregnancy induced by chronic disease, infection, or environmental exposures has been associated with neurodevelopmental conditions in observational study designs. OBJECTIVE To investigate causal effects of pregnancy inflammation on offspring neurodevelopment in the Norwegian Mother, Father...

K. Aagaard, A. Eliasen, J. R. Jepsen et al. · 0 citations

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