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Author

B. Gelb

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Open access Aug 2026

Rigosertib Reverses Hypertrophic Cardiomyopathy in Noonan Syndrome

It is suggested rigosertib normalizes and reverses RASopathy-associated HCM and other NS-associated syndromic features, supporting its development as a promising treatment for RAF1-associated HCM and, potentially, other RASopathy-dependent pathologies.

Levi Legler, K. Marchetti, Bing Xu et al. · 0 citations
Open access Jul 2026

Uniparental Disomy Reveals Hidden Genetic Causes of Congenital Heart Disease

TrioMix-UPD, an integrated short- and long-read sequencing framework for UPD detection and classification, is developed and established UPD as an underrecognized contributor to CHD.

Nahyun Kong, Javier Abello, Christopher J. Yoon et al. · 0 citations

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