Breast cancer remains a leading cause of cancer-related mortality among women, while recurrence, multidrug resistance, and systemic toxicity continue to limit therapeutic outcomes. Berberine (BBR), a natural isoquinoline alkaloid with chemo-photodynamic potential, exhibits promising anticancer activity; however, poor s...
I. Baidoo, Paromita Sarbadhikary, B. George· Nanoscale Advances· 0 citations
The findings indicate that the green synthesized AgNPs exhibit significant cytotoxic and apoptosis-inducing effects in HT-29 colorectal cancer cells, and further studies involving normal cell lines and in vivo models are required to validate their therapeutic potential.
Shobana Sampath, Archana Hari, B. George et al.· Discover Nano· 3 citations
The effectiveness of chemotherapy in colorectal cancer (CRC) is significantly reduced by acquired chemoresistance to 5-fluorouracil (5-FU), oxaliplatin and irinotecan. This structured narrative review synthesises mechanistic, preclinical, translational and clinical evidence underlying resistance to these agents. Distin...
D. Bartusik-Aebisher, Izabella Wilk, B. George et al.· Cells· 0 citations
It is demonstrated that chemo‐biodiversity provides a rational foundation for the discovery of next‐generation natural photosensitizers, and Harnessing nature's evolutionary molecular diversity offers new opportunities to develop safer, more effective, and clinically translatable photodynamic therapies.
I. Baidoo, H. Abrahamse, B. George· Chemistry and Biodiversity· 0 citations
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