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Oct 2026

The Gα-interacting protein RGS4 in dorsal root ganglia maintains molecular and behavioral maladaptations in murine pain models.

Regulator of G protein signaling 4 (RGS4) is a Gα subunit-interacting protein that modulates the functional responses of various G protein-coupled receptors (GPCRs) and that is present in several components of the nociceptive circuitry. Here, we found that RGS4 in lumbar dorsal root ganglia (DRGs) is required for the m...

R. Serafini, B. Giotti, A. Luebbers et al. · 0 citations
Open access Jul 2026

Cellular hallmarks and aging clock of the human lung parenchyma

Multiple cellular hallmarks of lung aging in human tissue are uncovered at single-cell and spatial resolution, including altered alveolar stemness, immune signaling, and macrophage respiration pathways, that may help assess lung biological age and disease risk.

Ke Xu, Grace S. Kim, A. Bhagwat et al. · 0 citations

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