Open access
Aug 2026
Spatial multi-omics reveals targetable immunosuppressive macrophage T-cell interactions in human AML bone marrow
This comprehensive spatial map of the AML bone marrow identified tripartite crosstalk between AML, macrophages, and T cells mediated by the Galectin-9 – CD44/TIM-3 axis as a key component of the immunosuppressive microenvironment.
M. van der Meulen, Emma S. Pool, A. Perzolli et al.
· bioRxiv · 0 citations