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Author

B. Gyawali

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2 papers indexed here

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Open access Sep 2026

Early termination of clinical trials enrolling patients with breast cancer: Reasons, determinants, and temporal patterns

Background The occurrence of clinical trial termination before planned completion (or “early termination” [ET]) remains poorly characterized in the breast cancer field. This study investigates the reasons, determinants, and temporal patterns of ET in breast cancer trials. Methods We conducted a cross-sectional study us...

G. M. Iannantuono, G. Daniele, Luca Mastrantoni et al. · 0 citations
Open access Sep 2026

(Neo)adjuvant approvals for solid tumors by the US Food and Drug Administration 2010-2023

Abstract Background (Neo)adjuvant systemic treatments aim to improve overall survival by reducing recurrence risk; however, there can be challenges, such as reliance on surrogate endpoints, censoring, loss to follow-up, and impact on quality of life. We examine the design, reporting, and outcomes of US Food and Drug Ad...

C. M. Valiente, A. Mittal, Dong-Sheng Tu et al. · 0 citations

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