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B. Heijmans

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Open access Oct 2026

Blood cell composition reveals distinct biological interpretation of DNA methylation age and age acceleration

Epigenetic clocks are widely applied biomarkers of biological age, but their biological underpinnings remain unclear. We previously showed that epigenetic clocks are affected by naïve and memory T cell proportions, suggesting blood cell composition as a potential driver. However, analysis of cell composition is complic...

Thomas H. Jonkman, Anne Richmond, R. Marioni et al. · 0 citations
Open access Aug 2026

DNA methylation signal of birthweight generalizes to high-risk pregnancies and is independent of genetic, maternal, and obstetric factors: a twin study

DNA methylation is associated with individual differences in birthweight in a high-risk clinical population of MC twins, independent of shared genetic, familial, maternal, and obstetric factors.

M. Sulaiman, L. Franken, J. A. Spekman et al. · 0 citations

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