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B. Heude

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Open access Aug 2026

Type, number and timing of family structure transitions and their association with internalizing and externalizing problems in early adolescence: evidence from the French EDEN cohort.

PURPOSE Family structure transitions affect adolescents' mental health, yet uncertainty remains about their type, frequency, and timing effects. This longitudinal study examines these transitions and their association with early adolescents' internalizing and externalizing problems. METHOD Using data from the French...

Mirna Naddour, M. Tafflet, B. Heude et al. · 0 citations
Open access Sep 2026

Maternal healthy lifestyle during pregnancy and offspring metabolic health phenotypes in childhood.

BACKGROUND AND AIM Maternal lifestyle factors during pregnancy may influence offspring risk of childhood overweight-obesity (OW-OB). Obesity is a heterogenous condition with different metabolic phenotypes; limited research on their associations with early-life exposures exists. We investigated associations of a composi...

A. M. Aubert, M. Schipper, Kathrin Guerlich et al. · 0 citations
Review Open access Aug 2026

Maternal Adverse Childhood Experiences and Child Socio-Emotional and Behavioural Outcomes: A Systematic Review of Prenatal Mechanisms.

Prenatal maternal depression and anxiety emerged as the most frequently studied mechanisms, showing some evidence of independent effects irrespective of postnatal factors, but most of the findings point towards a 'chain-of-risk' model, where prenatal mental health interacts with the postnatal environment.

Sara Avendano, Aicha Mourchidi, Susana Barbosa et al. · 0 citations
Open access Sep 2026

Genome-wide association meta-analysis of eating behavior traits revealed one susceptibility locus for emotional eating.

A meta-GWAS with seven studies of European ancestry identified for the first time a robust chromosomal region associated with emotional eating in seven studies, supporting the hypothesis that shared genetic factors may influence both eating behavior traits and obesity risk.

M. Muntaner, K. Horn, B. de Lauzon-Guillain et al. · 0 citations
Open access Sep 2026

Prenatal and childhood exposure to mixtures of endocrine-disrupting chemicals in association with measures of adiposity in childhood and adolescence.

Early-life exposure to EDC mixtures may reprogram metabolic and inflammatory pathways, predisposing children to obesity that persists into adolescence, and underscore the urgent need for policies preventing EDC exposure during critical developmental periods.

Nuria Güil-Oumrait, V. Midya, Sandra India-Aldana et al. · 0 citations
Open access Jul 2026

Placental DNA methylation captures shared and trait-specific genetic susceptibility across complex health conditions

A high-resolution placental mQTL resource is constructed and systematically investigated how placental DNAm relates to early- and later-life traits, and to shared vulnerability and complex interactions among them.

A. Cilleros-Portet, Itziar González-Moro, Hachem Sadikki et al. · 0 citations

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