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Author

B. Koo

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Open access Sep 2026

Dual solvent cavities and hydrogen-bond networks define the chromophore environment in a far-red/orange-sensing cyanobacteriochrome.

Cyanobacteriochromes (CBCRs) are bilin-binding photoreceptors that exhibit remarkable spectral diversity and mediate light-dependent signaling in cyanobacteria. Far-red/orange-sensing CBCRs (froCBCRs) have attracted interest because of their unusually red-shifted absorption properties, yet structural information for th...

Hee Wook Yang, Youngran Kim, Xin-Wei Liu et al. · 0 citations
Open access Sep 2026

First evidence for TIGR-Tas activity in a photosynthetic eukaryote

Initial evidence is provided that TIGR–Tas can act on the nuclear genome of a photosynthetic eukaryote, and dsNHO-assisted recovery of sequence alterations is not restricted to conventional CRISPR– Cas nucleases.

Jaeyeon Lee, Kyeongjun Kim, Hyeonmin Ryu et al. · 0 citations
Review Open access Aug 2026

Patient-derived organoids in pancreatic cancer: Advances and applications in precision oncology

This review summarizes recent advances in PDAC organoid technology, including tissue acquisition, organoid establishment, molecular characterization, biobanking, and integration with cancer-associated fibroblasts, immune cells, endothelial cells, CRISPR/Cas9 genome editing, assembloid systems, and microfluidic organ-on...

Hee-Seung Lee, B. Koo · 0 citations
Open access Aug 2026

Structural basis of HSL3/NUT receptor kinase-mediated recognition of a disulfide-constrained phytocytokine.

Plant receptor kinases perceive diverse peptide signals to coordinate stress responses and developmental programs. The HAESA-LIKE 3 (HSL3/NUT) receptor recognizes CTNIP/SCREW phytocytokines-disulfide-constrained peptides that regulate immune signaling and stress adaptation. However, how HSL3 distinguishes these structu...

Se-Jin Choi, Hoseong Jung, Hyeonmin Ryu et al. · 0 citations

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