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Author

B. Mathew

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4 papers indexed here

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Review Open access Oct 2026

Beyond Single-Target Therapy: Dual-Acting Cannabinoid Type-2 Receptor Modulation in Neurological Disorders.

Neurological disorders such as Alzheimer's disease, Parkinson's disease, and neuroinflammatory conditions involve complex, interconnected mechanisms, including neuroinflammation, oxidative stress, cholinergic dysfunction, and synaptic impairment. The cannabinoid type-2 receptor (CB2R), primarily expressed in immune and...

Sandeep K. Bindra, T. Rangarajan, D. G. T. Parambi et al. · 0 citations
Review Open access Sep 2026

Hepatocellular carcinoma therapy and mechanism of action: current perspectives

Purpose: Hepatocellular carcinoma (HCC) is the most common primary liver cancer, accounting for nearly 90% of cases and causing over 700,000 deaths annually. Increasing evidence indicates that dysregulated lipid metabolism plays a critical role in hepatocarcinogenesis by promoting tumor initiation, progression, metasta...

Sandeep K. Bindra, Sunil Kumar, Athira Sujathan Nair et al. · 0 citations
Review Open access Sep 2026

Structural features, activity relationships, and synthetic strategies of indole-based derivatives as antitubercular agents targeting mycolic acid biosynthesis

Tuberculosis (TB) is a severe airborne infectious disease caused by Mycobacterium tuberculosis ( M. tb ), primarily impacting the lungs and other organs. Antimicrobial resistance in TB is an emerging problem that requires immediate treatment and management. It is difficult to cure tuberculosis as there are increa...

Sandeep Bindra, Chetna Amrodiya, M. Abdelgawad et al. · 0 citations
Open access Aug 2026

Integrative network pharmacology and molecular modeling approaches reveal the therapeutic potential of Syzygium samarangense phytocompounds against diabetes retinopathy

These multi-target interactions suggest that S. samarangense phytochemicals can modulate key DR-associated pathways, and exhibits promising multi-target activity against Diabetes retinopathy.

Arun Kandhan, B. Mathew, Sundarrajan Thirugnanasambandam · 0 citations

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