Mechanistic insights into mitochondrial dynamics in HD are summarized, highlighting how mutant huntingtin (mHTT) impairs mitochondrial biogenesis and morphology, disrupts Drp1-dependent fission, compromises fusion, transport and organelle crosstalk with the endoplasmic reticulum, and disrupts mitochondrial quality cont...
B. Paiva, A. Cristina Rego· Journal of Huntington's Dise...· 0 citations
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