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B. Paiva

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Review Open access Aug 2026

Mitochondrial dynamics in Huntington's disease.

Mechanistic insights into mitochondrial dynamics in HD are summarized, highlighting how mutant huntingtin (mHTT) impairs mitochondrial biogenesis and morphology, disrupts Drp1-dependent fission, compromises fusion, transport and organelle crosstalk with the endoplasmic reticulum, and disrupts mitochondrial quality cont...

B. Paiva, A. Cristina Rego · 0 citations

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