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Author

B. Popova

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Review Open access Sep 2026

Breaking the proteasome balance: α-synuclein and the ubiquitin-proteasome system

Aging is the major risk factor for synucleinopathies, including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy. However, the molecular mechanisms linking aging to. α-Synuclein cytotoxicity remain incompletely understood. The progressive decline of proteostasis is central among these mechani...

Tariq T. Ali, B. Popova, G. Braus · 0 citations

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